Recombinant Human BD-3
产品名称： Recombinant Human BD-3
英文名称： Recombinant Human BD-3
产品编号： 300-52
产品价格： 0
产品产地： USA
品牌商标： PEPROTECH
更新时间： null
使用范围： null
上海研卉生物科技有限公司
- 联系人 :
- 地址 : 上海市嘉定区叶城路1288号
- 邮编 :
- 所在区域 : 上海
- 电话 : 187****6455
- 传真 : 021-69000211
- 邮箱 : yanhuibio@163.com
产品编号:
300-52
别名:
beta-defensin-3, DEFB3, DEFB103A
描述:
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human BD-3 is a 5.1 kDa protein containing 45 amino acid residues.
氨基酸序列:
GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
来源:
E.coli
纯度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli.
交叉反应:
Bacteria, Mouse, Virus
原产国:
USA
仅用于研究。不适用于诊断或治疗。