IL12B (Human) Recombinant Protein
产品名称： IL12B (Human) Recombinant Protein
英文名称： IL12B (Human) Recombinant Protein
产品编号： P3813
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human IL12B (NP_002178.2, 23 a.a. - 328 a.a.) partial recombinant protein expressed in Escherichia coli.
- Sequence:
- IWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITWTLDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQKEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERVRGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVICRKNASISVRAQDRYYSSSWSEWASVPCS
- Form:
- Liquid
- Preparation Method:
- Escherichia coli expression system
- Purity:
- > 95% by SDS-PAGE
- Storage Buffer:
- In PBS (50% glycerol)
- Storage Instruction:
- Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 10% SDS-PAGE Result
- Application Image
- SDS-PAGE
- Entrez GeneID:
- 3593
- Protein Accession#:
- NP_002178.2
- Gene Name:
- IL12B
- Gene Alias:
- CLMF,CLMF2,IL-12B,NKSF,NKSF2
- Gene Description:
- interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq
- Other Designations:
- IL12, subunit p40,OTTHUMP00000160820,cytotoxic lymphocyte maturation factor 2, p40,interleukin 12, p40,interleukin 12B,interleukin-12 beta chain,natural killer cell stimulatory factor, 40 kD subunit,natural killer cell stimulatory factor-2
- Related Disease
- Abscess
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Adenocarcinoma
- Aggressive Periodontitis
- AIDS Dementia Complex
- Alcoholism
- Anemia
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Autoimmune Diseases
- Barrett Esophagus
- Behcet Syndrome
- Brain Neoplasms
- Bronchial Hyperreactivity
- Bronchiolitis, Viral