IGSF16,免疫球蛋白超家族成员16抗体

产品编号HZ-9203R
英文名称IGSF16
中文名称免疫球蛋白超家族成员16抗体
别 名CD300 antigen-like family member C; CD300c; CLM-6; CLM6_HUMAN; CMRF-35; CMRF35 leukocyte immunoglobulin-like receptor; CMRF35-A1; CMRF35-like molecule 6; CMRF35A leukocyte immunoglobulin-like receptor; IgSF16; Immunoglobulin superfamily member 16; LIR.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 t-淋巴细胞 b-淋巴细胞
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
IGSF16,免疫球蛋白超家族成员16抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量23kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human IGSF16/CD300C
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
IGSF16,免疫球蛋白超家族成员16抗体PubMedPubMed
产品介绍background:
CD300C (), also known as CLM-6 (CMRF35-like molecule 6), is a 224 amino acid single-pass type I membrane protein that is present on the surface of neutrophils, monocytes and a select proportion of peripheral blood B and T lymphocytes. CD300C contains two potential N-gylcosylation sites, a potential O-glycosylated hinge-like region and an Ig-like V-type (immunoglobulin-like) domain that is very similar to the Fc receptor for polymeric IgA and IgM. The gene encoding CD300C is localized to a region on human chromosome 17 that harbors a susceptilibty locus for psoriasis, dermatitis and rheumatoid arthritis, suggesting a possible involvement of CD300C with these conditions.

Subcellular Location:
Cell membrane

Tissue Specificity:
Present on the surface of monocytes, neutrophils, a proportion of peripheral blood T- and B-lymphocytes and lymphocytic cell lines.

IGSF16,免疫球蛋白超家族成员16抗体Similarity:
Belongs to the CD300 family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene ID:
10871

Database links:
Entrez Gene: 10871 Human
Omim: 606786 Human
SwissProt: Q08708 Human
Unigene: 2605 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.