CDC2L1 (N-term) Peptide
产品名称： CDC2L1 (N-term) Peptide
英文名称： CDC2L1 (N-term) Peptide
产品编号： P2516
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CDC2L1.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human CDC2L1.
- Host:
- Rabbit
- Reactivity:
- Hamster, Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis.
Chen S, Yin X, Zhu X, Yan J, Ji S, Chen C, Cai M, Zhang S, Zong H, Hu Y, Yuan Z, Shen Z, Gu J.J Biol Chem. 2003 May 30;278(22):20029-36. Epub 2003 Mar 6.
- 2.
- CDK11 complexes promote pre-mRNA splicing.
Hu D, Mayeda A, Trembley JH, Lahti JM, Kidd VJ.J Biol Chem. 2003 Mar 7;278(10):8623-9. Epub 2002 Dec 24.
- 3.
- Identification and characterization of a novel cell cycle-regulated internal ribosome entry site.
Cornelis S, Bruynooghe Y, Denecker G, Van Huffel S, Tinton S, Beyaert R.Mol Cell. 2000 Apr;5(4):597-605.
- Application Image
- Western Blot
- Immunohistochemistry
- ELISA
- Entrez GeneID:
- 984
- Protein Accession#:
- NP_001778;P21127
- Gene Name:
- CDC2L1
- Gene Alias:
- CDC2L2,CDK11,CDK11-p110,CDK11-p46,CDK11-p58,CLK-1,FLJ59152,PK58,p58,p58CDC2L1,p58CLK-1
- Gene Description:
- cell division cycle 2-like 1 (PITSLRE proteins)
- Omim ID:
- 176873
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq
- Other Designations:
- CDC-related protein kinase p58,OTTHUMP00000000760,OTTHUMP00000000767,OTTHUMP00000000768,PITSLRE serine/threonine-protein kinase CDC2L1,PITSLREA,cell division cycle 2-like 2 (PITSLRE proteins),cell division cycle 2-like protein kinase 1,galactosyltransfera