IL1B polyclonal antibody-抗体-抗体-生物在线
IL1B polyclonal antibody

IL1B polyclonal antibody

商家询价

产品名称: IL1B polyclonal antibody

英文名称: IL1B polyclonal antibody

产品编号: PAB11294

产品价格: null

产品产地: 台湾

品牌商标: Abnova

更新时间: null

使用范围:

亚诺法生技股份有限公司(Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
  • 电话 : +886-920**1152
  • 传真 : +886-2-8751-1186
  • 邮箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant IL1B.
  • Immunogen:
  • Recombinant protein corresponding to 153 amino acids of human IL1B.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • The MW of the recombinant IL-1beta was 17,000 with the n-terminal amino acid at position alanine 117. This is the cleavage site generated by the IL-1beta converting enzyme (ICE, capase-1).
  • Form:
  • Liquid
  • Storage Buffer:
  • In 20 mM KH2PO4, 150 mM NaCl, pH 7.2
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • ELISA (1:200-1:1000)
    Western Blot (1:100-1:200)
    Immunocytochemistry (1:200)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)(1:100-1:200)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Immunoblotting of IL1B polyclonal antibody (Cat # PAB11294) was used at a 1 : 200 dilution incubated 1 h at room temperature to detect dog IL1B by Western blot.
    Lane 1 and 2 were loaded with 2.5 ug and 500 ng of dog IL1B respectively.
    The molecular weight of the detected band is estimated by comparison to molecular weight markers (not shown).
    Detection occurred using a 1 : 3,000 dilution of IRDye™800 conjugated Donkey anti-Rabbit IgG for 1h at room temperature.
    LICOR's Odyssey® Infrared Imaging System was used to scan and process the image.
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3553
  • Gene Name:
  • IL1B
  • Gene Alias:
  • IL-1,IL1-BETA,IL1F2
  • Gene Description:
  • interleukin 1, beta
  • Gene Summary:
  • The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq
  • Other Designations:
  • catabolin,preinterleukin 1 beta,pro-interleukin-1-beta
  • Interactome
  • Related Disease