PXN polyclonal antibody
产品名称： PXN polyclonal antibody
英文名称： PXN polyclonal antibody
产品编号： PAB4491
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152
- 传真 : +886-2-8751-1186
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PXN.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human PXN.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1 (1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Paxillin-beta-catenin interactions are involved in Rac/Cdc42-mediated endothelial barrier-protective response to oxidized phospholipids.
Birukova AA, Malyukova I, Poroyko V, Birukov KG.Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L199-211. Epub 2007 May 18.
- 2.
- RACK1 regulates Src activity and modulates paxillin dynamics during cell migration.
Doan AT, Huttenlocher A.Exp Cell Res. 2007 Jul 15;313(12):2667-79. Epub 2007 May 18.
- 3.
- Paxillin and ponsin interact in nascent costameres of muscle cells.
Gehmlich K, Pinotsis N, Hayess K, van der Ven PF, Milting H, El Banayosy A, Korfer R, Wilmanns M, Ehler E, Furst DO.J Mol Biol. 2007 Jun 8;369(3):665-82. Epub 2007 Mar 24.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of PXN polyclonal antibody (Cat # PAB4491) in Y-79 cell line lysates (35 ug/lane). PXN (arrow) was detected using the purified PXN polyclonal antibody (Cat # PAB4491) (1 : 60 dilution).
- Western Blot (Transfected lysate)
- Western blot analysis of PXN (arrow) using rabbit PXN polyclonal antibody (Cat # PAB4491). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PXN gene (Lane 2) (Origene Technologies).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with PXN polyclonal antibody (Cat # PAB4491) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated .
- Interactome
- Related Disease